Comparative Effectiveness Research


A survey of informatics platforms that enable distributed comparative effectiveness research using multi-institutional heterogenous clinical data

The goal of this manuscript is to help investigators understand why informatics platforms are required and to compare and contrast six, large-scale, recently funded, CER-focused informatics platform development efforts. We identified six generic steps that are necessary in any distributed, multi-institutional CER project: data identification, extraction, modeling, aggregation, analysis, and dissemination.


CER Hub: An informatics platform for conducting comparative effectiveness research using multi-institutional, heterogeneous, electronic clinical data

CER requires coordinated and scalable methods for extracting, aggregating, and analyzing complex, multi-institutional clinical data. By offering a range of informatics tools integrated into a framework for conducting studies using EHR data, the CER Hub provides a solution to the challenges of multi-institutional research using electronic medical record data.